HIV-Associated Facial Lipoatrophy

Dermatologic Surgery

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2002 Abstract

0211-979 James

James J, Carruthers A, Carruthers J.

HIV-associated facial lipoatrophy. Dermatol Surg. 2002 Nov;28(11):979-86. PMID: 12460289

Division of Dermatology and Department of Ophthalmology, University of British Columbia, Vancouver,British Columbia, Canada.

BACKGROUND:
HIV-infected individuals are living long, healthy lives. They are now concerned with less life-threatening problems, especially lipodystrophy.

OBJECTIVE:
To review the current state of our knowledge about lipodystrophy in HIV-infected individuals.

METHODS:
The literature was reviewed and analyzed for relevant information. In addition, our clinical experience of managing such individuals was utilized.

RESULTS:
Lipodystrophy and facial lipoatrophy and their relationship to HIV-infection are discussed. Their differences are noted. The spectrum of appearance in individuals with facial lipoatrophy is described and a severity scale suggested which should be of value in assessing the results of treatment.

CONCLUSION:
Lipodystrophy and lipoatrophy are intimately related to infection with HIV. In consequence, facial lipoatrophy is a major stigma for HIV-infected individuals and can have dramatic effects on their self-esteem and socialization. Effective treatment is essential.

Publication Types:
Review
Review, Tutorial

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